2013 EDITION.English version of the notice on September 28, 2012 sixteenth revised Japanese Pharmacopoeia first Supplement. The Ministry of Health, Labor and Welfare, the listing table of contents, foreword, General Rules, herbal General, General Rules for Preparations, general test method, drug monographs, reference infrared absorption spectrum, see ultraviolet-visible absorption spectrum, reference information, an index. Main contents pharmaceuticals new listing 77 items in each row, and listing the Delete 4 items, and partial revision 176 items. Newly added the 2.62 mass spectrometry and 2.63 inductively coupled plasma emission spectrometry and inductively coupled plasma mass spectrometry to general test method. Among the general test method, which has been amended are as follows. 2.22 fluorometry 2.47 osmometry (osmolality measurement method) 2.49 polarimetry measurement method 3.01 bulk density and tap density measurement method 4.01 endotoxin test method 6.10 dissolution test method Standard: newly listed were those 18 dishes. as an appendix, pharmaceuticals item list of each Article revision item, we have listed the standard product list, etc. documentation.